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KMID : 0604520130390010019
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Journal of the Society of Cosmetic Scientists of Korea
2013 Volume.39 No. 1 p.19 ~ p.24
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Biological Potential of Enzymatic and Polyphenol Extracts from Ecklonia cava
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Lee Su-Min
Kim Jin-Eun
Oh Myoung-Jin
Lee Joo-Dong
Jeon Yuo-Jin
Kim Bo-Ra
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Abstract
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To investigate the efficacy of enzymatic extract of Ecklonia cava and its polyphenol extract (AG-DK) as cosmetic ingredients, the anti-oxidative effect, anti-glycation effect, anti-melanogenic effect, and anti-inflammatory effect of the extracts were evaluated in vitro. The enzymatic extract of E. cava (SC50 42.9 ppm) and AG-DK (SC50 6.4 ppm) showed a strong DPPH free radical scavenging activity. The anti-glycation ability of the enzymatic extract of E. cava and AG-DK was tested using bovine serum albumin (BSA), which inhibited the formation of advanced glycationend-products (AGEs) in the BSA/glucose system. The enzymatic extract of E. cava (IC50 97.2 ppm) and AG-DK (IC507 ppm) had inhibitory effects on tyrosinase activity. Moreover, the enzymatic extract of E. cava and AG-DK had an anti-inflammatory effect through the inhibition of nitricoxide (NO) and prostaglandin E2 (PGE2). These findings suggest that the enzymatic extract of E. cava and AG-DK can be applied to skin-care products as cosmetic ingredients.
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KEYWORD
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Ecklonia cava extracts, anti-oxidant, anti-glycation, tyrosinase inhibition, anti-inflammation
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